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Medications for weight-loss
Reading time: approx. 4 minutes
Editors SeeMe-nopause
Editors SeeMe-nopause
Latest update: 06-02-2025
Reading time: approx. 4 minutes

What are the differences between weight loss medications Wegovy, Saxenda and Mounjaro?

During menopause, your body goes through major hormonal changes, decreasing the amount of hormones it makes. Progesterone levels usually drop faster than oestrogen. This can cause more oestrogen in relation to progesterone (oestrogen dominance). Elevated oestrogen levels can lead to more fat storage. Factors such as sleep problems, increased stress and loss of muscle mass can also contribute to weight gain in menopause.  

Balancing the calories you eat and regular physical activity are key to maintaining a healthy weight. If this isn’t enough, weight loss medications can support your efforts to lose weight and live a healthier life. When it comes to weight loss medications, Wegovy and Saxenda are two names that often come up. Mounjaro, originally a diabetes medication, has recently been approved for weight loss. How do you decide which weight loss medication could be right for you? We've broken down the key differences to help you make an informed choice.  

How do they work?

Mounjaro, Wegovy and Saxenda all offer a new approach to weight management. Mounjaro, originally a diabetes medication, has now also been approved for weight loss. It is an injectable medicine that is usually taken once a week. Mounjaro can help individuals who have been unsuccessful losing weight through other methods lose up to 10% or more of their total body weight.  

Saxenda and Wegovy are also effective weight loss medications. They promote weight loss by controlling your appetite and making you feel fuller for longer. Saxenda and Wegovy are given as an injection under the skin (subcutaneous injection). Wegovy is administered once a week according to a dose escalation schedule and can lead to a weight loss of 20%. Saxenda is a daily injection. The dose should be increased weekly according to a dose escalation schedule. Saxenda can help users achieve a 10% weight loss when paired with a healthy lifestyle. 

Before making a choice, it is important to compare all options carefully and consult with a healthcare provider to determine which medication is best for your needs. Remember a healthy diet and physical activity should be part of your weight loss plan for lasting results. 

Comparison table

Side effects you should know about

Just like all medicines, Mounjaro (Zepbound), Wegovy and Saxenda can cause side effects. You may experience nausea, vomiting, diarrhoea and constipation. Most side effects are usually only temporary and will disappear once the body adjusts to the medicine. Talk to your doctor if you have any concerns. 

Conclusion

Deciding which of the three medications to take is a personal choice that depends on your health status and weight loss goals. Mounjaro, Wegovy and Saxenda all offer effective solutions for weight loss, but it is important to make an informed decision with your doctor's guidance.

Disclaimer

This article is for informational purposes only and should not be considered professional medical advice. Always consult a doctor or other qualified healthcare provider with questions you may have about a medical condition or treatment.

Control your weight with the right treatment

With SeeMe-nopause, you can choose a treatment from the comfort of your home and receive a prescription within 48 hours. If the medication is not suitable for you, a doctor will advise you on the best course of action. The pharmacy will deliver the medication to your doorstep, quickly and easily.

Sources

https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/t/tirzepatide 

Tirzepatide (Mounjaro) | Overgewicht Nederland 

New Drug: Tirzepatide (Mounjaro™) - PubMed (nih.gov)  https://pubmed.ncbi.nlm.nih.gov/36751934/

A Mini-Review - PMC (nih.gov) https://pmc.ncbi.nlm.nih.gov/articles/PMC9268041/ 

Weight loss efficiency and safety of tirzepatide: Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity:A Review Review - PMC (nih.gov) 

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