Blissel is a vaginal gel containing the bio-identical hormone estriol. This hormone closely resembles the oestrogen naturally produced by your body. During menopause, oestrogen levels decline, which can result in symptoms such as recurrent thrush, urinary tract infections, vaginal dryness, or discharge. Blissel is a hormone replacement therapy designed to relieve these symptoms by improving the health and elasticity of the vaginal lining. The gel works locally and is only available with a prescription.
Hormone replacement therapy
Blissel
Vaginal gel
In short
- For vaginal dryness, recurrent thrush, or urinary tract infections
- May help with vaginal dryness, urinary incontinence, and vaginal discharge
- Vaginal gel with bio-identical estriol
- Prescription-only medicine
What is Blissel?
What can you expect from Blissel?
Blissel acts directly on the vaginal lining, helping to alleviate recurrent thrush, urinary tract infections, and vaginal dryness. Most users notice an improvement in their symptoms within a few weeks.
When should I use Blissel?
Blissel is typically used daily at the start of treatment, with the frequency reduced as advised by your doctor. The package leaflet contains detailed information about this product. Make sure to read the leaflet before using the product.
For which symptoms should you use Blissel?
- Recurrent thrush or urinary tract infections
- Vaginal dryness
Blissel may also help with:
- Vaginal discharge
- Urinary incontinence
Do not use Blissel if you:
- Are allergic to estriol or any other ingredients in the gel
- Have unexplained vaginal bleeding
- Have an untreated vaginal infection
- Are pregnant or breastfeeding
- Have a severe liver condition
Inform your doctor who prescribes the medication if you are taking other medicines.
Possible side effects of Blissel
Common (affecting 1 to 10 out of 100 users):
Vaginal discharge, itching, or irritation
Uncommon (affecting 1 to 10 out of 1,000 users):
Pain or discomfort during application
Rare (affecting fewer than 1 out of 1,000 users):
Allergic reactions such as rash or swelling
In rare cases, these side effects can lead to serious symptoms, such as an allergic reaction with swelling of the face, lips, or throat, or difficulty breathing. If this occurs, contact a doctor immediately.
Risks of hormone replacement therapy
The use of medication containing hormones can carry risks; however, this does not apply to vaginal hormone replacement therapy. Vaginal administration of hormone replacement therapy is entirely safe and free from risk because the hormones are minimally absorbed into the bloodstream. Studies indicate no increased risk of thrombosis, strokes, or cancer.
For a complete list of side effects, consult the package leaflet.
Scientific references
Menopause Hormone Therapy and Urinary Symptoms: A Systematic Review - PubMed
Vaginal Oestrogen Therapy Use and Survival in Females with Breast Cancer - PubMed
2016 IMS Recommendations on women's midlife health and menopause hormone therapy - PubMed
Management of unscheduled bleeding on hormone replacement therapy (HRT) - British Menopause Society
Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long? - PubMed
Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment - PubMed
Updates in Hormone Replacement Therapy for Survivors of Gynecologic Cancers - PMC
Oestrogen-based therapies for menopausal symptoms - PubMed
The 2022 hormone therapy position statement of The North American Menopause Society - PubMed
Hormone Therapy in Menopause - PubMed
Hormoonsuppletietherapie en het risico op veneuze trombo-embolie | Stichting Geneesmiddelenbulletin
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| Dosage & pack size | Price |
|---|---|
| Blissel 50 mg gel | £44.00 |
Medically reviewed by
Dr. Erik KnauffRegistration number:: 89059736001
Patient Information Leaflet
Read the patient information leaflet carefully before using Blissel.
Blissel helps with
Frequently asked questions
Will my treatment be covered?
This depends on your health insurance provider. We recommend you check with your own insurance company. Supplements are not usually covered.
What is a consultation and how does it work?
During the consultation, you will complete a comprehensive medical questionnaire. You can also state your preferred type of treatment. Based on your answers, a doctor will prepare a treatment plan for you within 48 hours. If you approve this plan, a pharmacy will dispatch the products to your home within 3 days.
How long will it take to receive my order?
Our partner pharmacies will dispatch your order within 3 days. You can then typically start your treatment straight away.
Are there delivery charges?
For prescription medicines, delivery is included in the price. For over-the-counter products, there is a delivery charge of £4.21. We offer free delivery on orders over £40. If your order includes both, delivery is free.
Can I change, cancel or return my order?
Unfortunately, once an order has been placed, it cannot be changed. If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.