Common (in more than 1 in 10 users):
Sometimes (in 1 to 10 out of 100 users):
Headache
Nausea
Abdominal pain
Mood changes
Rarely (in less than 1 in 1,000 users):
Serious but rare side effects: In rare cases, these side effects can lead to serious conditions, such as thrombosis or heart problems. Always contact a doctor immediately in such situations.
Risks of hormone replacement therapy
The use of medication carries risks, and this is also true for menopausal hormone replacement therapy. When using oestrogen through the skin:
If you still have a uterus, oestrogen must be combined with progesterone/progestogen. Otherwise, there is an increased risk of uterine cancer. For hormone replacement therapy involving oestrogen and progesterone/progestogen:
If you no longer have a uterus and use oestrogen alone, this increased risk of breast cancer is minimal or non-existent.
Recent studies indicate that menopausal hormone replacement therapy (when started before the age of 60) can have protective effects in addition to its risks. This includes benefits for certain types of cancer, osteoporosis, and diabetes.
For a complete list of side effects, consult the package leaflet.