Imvaggis is a vaginal tablet containing the bio-identical hormone estriol. This hormone is similar to the oestrogen naturally produced by your body. During menopause, oestrogen levels decline, which can result in symptoms such as recurrent thrush or urinary tract infections, vaginal dryness, or discharge. Imvaggis is a hormone replacement therapy designed to relieve these symptoms by improving the health and elasticity of the vaginal lining. The product works locally within the vagina and is only available with a prescription.
Imvaggis

In short
- For vaginal dryness, recurrent thrush or urinary tract infections
- May help with urinary incontinence, vaginal discharge
- Vaginal tablet with bio-identical estriol
- Prescription-only medication
What is Imvaggis?
What can you expect from Imvaggis?
Imvaggis works by restoring and strengthening the vaginal lining. It is a vaginal tablet that is inserted into the vagina. Symptoms may begin to improve within a few weeks. Imvaggis acts locally and does not have noticeable effects on the rest of the body.
When should I use Imvaggis?
Typically, Imvaggis is used daily at first, and then less frequently as directed by your doctor. The package leaflet contains all the relevant information about this product. Ensure you read the leaflet before using the product.
For which symptoms is Imvaggis used?
- Recurrent thrush or urinary tract infections
- Vaginal dryness
Imvaggis may also help with:
- Vaginal discharge
- Urinary incontinence
Do not use Imvaggis if you:
- Are allergic to estriol or any other ingredients in this product
- Are pregnant or breastfeeding
- Have an untreated vaginal infection
- Have or have had breast cancer, or another hormone-sensitive tumour (unless otherwise advised by your doctor)
- Have unexplained vaginal bleeding
Inform your doctor prescribing the medication if you are taking any other medicines.
Possible side effects of Imvaggis
Common (affecting fewer than 1 in 10 women):
Vaginal itching, irritation, or discharge
Uncommon (affecting fewer than 1 in 100 women):
Pain or discomfort during insertion
Rare (affecting fewer than 1 in 1,000 women):
Skin rash or allergic reaction
In rare cases, these side effects may result in serious symptoms, such as an allergic reaction causing swelling of the face, lips, or throat, or difficulty breathing. If this occurs, contact a doctor immediately.
Risks of hormone replacement therapy
The use of medication containing hormones can carry risks; however, this does not apply to vaginal hormone replacement therapy. Vaginal administration of hormone replacement therapy is entirely safe and free from risk because the hormones are minimally absorbed into the bloodstream. Studies indicate no increased risk of thrombosis, strokes, or cancer.
For a complete list of side effects, please refer to the package leaflet.
Scientific references
Menopause hormone therapy and urinary symptoms: a systematic review - PubMed
Vaginal Oestrogen Therapy Use and Survival in Females With Breast Cancer - PubMed
2016 IMS Recommendations on women's midlife health and menopause hormone therapy - PubMed
Management of unscheduled bleeding on hormone replacement therapy (HRT) - British Menopause Society
Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long? - PubMed
Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment - PubMed
Updates in Hormone Replacement Therapy for Survivors of Gynecologic Cancers - PMC
Oestrogen-based therapies for menopausal symptoms - PubMed
The 2022 hormone therapy position statement of The North American Menopause Society - PubMed
Hormone Therapy in Menopause - PubMed
Hormoonsuppletietherapie en het risico op veneuze trombo-embolie | Stichting Geneesmiddelenbulletin
What does Imvaggis cost?
| Dosage & pack size | Price |
|---|---|
| Imvaggis 0.03mg | £39.00 |
Medically reviewed by

Patient Information Leaflet
Read the patient information leaflet carefully before using Imvaggis.
Imvaggis helps with
Frequently asked questions
Will my treatment be covered?
This depends on your health insurance provider. We recommend you check with your own insurance company. Supplements are not usually covered.
What is a consultation and how does it work?
During the consultation, you will complete a comprehensive medical questionnaire. You can also state your preferred type of treatment. Based on your answers, a doctor will prepare a treatment plan for you within 48 hours. If you approve this plan, a pharmacy will dispatch the products to your home within 3 days.
How long will it take to receive my order?
Our partner pharmacies will dispatch your order within 3 days. You can then typically start your treatment straight away.
Are there delivery charges?
For prescription medicines, delivery is included in the price. For over-the-counter products, there is a delivery charge of £4.21. We offer free delivery on orders over £40. If your order includes both, delivery is free.
Can I change, cancel or return my order?
Unfortunately, once an order has been placed, it cannot be changed. If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.