ProductMirena levonorgestrel IUD

Hormone replacement therapy

Mirena levonorgestrel IUD

Intrauterine device (IUD)

In short

For heavy menstrual bleeding and as contraception
Can help alleviate menstrual pain
Hormonal IUD containing levonorgestrel (synthetic)
Protects the uterine lining from undesirable thickening when using oestrogen for menopausal symptoms
Prescription-only medicine

What is Mirena?

Mirena is a hormonal IUD that releases the hormone levonorgestrel directly into the uterus. It is designed for women who experience heavy menstrual bleeding, are seeking a dependable form of contraception, or require protection for their uterine lining while using oestrogen for menopausal symptoms.

The hormone is released locally, which thins the uterine lining. This can lead to lighter bleeding and reduced menstrual pain. Mirena must be fitted by a doctor or another qualified healthcare professional.

What can you expect from Mirena?

When should I use Mirena?

Mirena is fitted once by a doctor.
After insertion, the IUD remains effective for up to 8 years.
Irregular bleeding during the first few months is normal.

Mirena is used for:

Contraception
Treatment of heavy menstrual bleeding
Protection of the uterine lining when using oestrogen in menopausal therapy

The patient information leaflet contains all the details about this product. Ensure you read the leaflet before using the product.

For which symptoms is Mirena used?

It is used for:

Heavy menstrual bleeding
Menstrual pain
Contraception
Uterine lining protection during hormone replacement therapy

It is not intended for:

Hot flushes
Night sweats
Mood swings

Do not use Mirena if you:

Are pregnant or suspect you may be pregnant
Have an infection in the pelvis, uterus, or cervix
Have or have had an oestrogen- or progestogen-sensitive tumour, such as breast cancer
Have unexplained vaginal bleeding
Have a severe liver condition
Have a uterine abnormality that prevents insertion
Have recently experienced an infection or inflammation following childbirth
Are allergic to levonorgestrel or any of the excipients

This is not an exhaustive list. The patient information leaflet contains all contraindications and warnings.

Consult your doctor if you are taking other medications.

Possible side effects of Mirena

Common (affecting more than 1 in 10 users):

Irregular bleeding or reduced or no menstruation
No menstruation at all

Occasional (affecting 1 in 100 to 1 in 10 users):

Headache
Abdominal pain
Mood changes
Tender or painful breasts
Acne

Rare (affecting fewer than 1 in 1,000 users):

IUD displacement or expulsion
Pelvic infection
Uterine wall perforation

Serious but rare side effects: In rare instances, these side effects may lead to severe symptoms, such as high fever, severe abdominal pain, or persistent bleeding. Always contact a doctor immediately in such cases.

Risks of hormone replacement therapy

The use of medication carries risks, and this is also true for menopausal hormone replacement therapy. Progesterone/progestogen is prescribed as a supplement to oestrogen treatment if you still have a uterus, as there is otherwise an increased risk of uterine cancer. Are you using a product containing oestrogen and still have a uterus? Check the potential risks of using progesterone/progestogen in combination with oestrogen on the specific product page.

For a complete list of side effects, refer to the patient information leaflet.

Scientific sources

levonorgestrel (IUD)

levonorgestrel IUD | Apotheek.nl

PATIENT INFORMATION LEAFLET

Efficacy of Micronized Progesterone for Sleep: A Systematic Review and Meta-analysis of Randomized Controlled Trial Data - PubMed

Effects of progestogens used in menopause hormone therapy on the normal breast and benign breast disease in postmenopausal women - PubMed

Menopausal hormone therapy and women's health: An umbrella review - PubMed

Different regimens of menopausal hormone therapy for improving sleep quality: a systematic review and meta-analysis - PubMed

Review of menopausal hormone therapy with estradiol and progesterone versus other estrogens and progestins - PubMed

Management of Menopausal Symptoms: A Review - PubMed

Hormone therapy for sexual function in perimenopausal and postmenopausal women - PubMed

Progestogens for endometrial protection in combined menopausal hormone therapy: A systematic review - PubMed

Risks and benefits of hormone therapy after menopause for cognitive decline and dementia: A conceptual review - PubMed

Metabolism of progestogens used for contraception and menopausal hormone therapy - PubMed

Neuroendocrine mechanisms of mood disorders during menopause transition: A narrative review and future perspectives - PubMed

Progestogens in Menopausal Hormone Therapy: A Double-Edged Sword - PubMed

2016 IMS Recommendations on women's midlife health and menopause hormone therapy - PubMed

Menopausal symptoms and treatment-related effects of estrogen and progestin in the Women's Health Initiative - PubMed

Management of unscheduled bleeding on hormone replacement therapy (HRT) - British Menopause Society

Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study - PubMed

Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long? - PubMed

Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment - PubMed

FSRH Guideline Contraception for Women Aged Over 40 Years / fsrh-guideline-contraception-for-women-aged-over-40-years.pdf / PDF4PRO

Updates in Hormone Replacement Therapy for Survivors of Gynecologic Cancers - PMC

Oestrogen-based therapies for menopausal symptoms - PubMed

The 2022 hormone therapy position statement of The North American Menopause Society - PubMed

Hormone Therapy in Menopause - PubMed

Effect of oral and transdermal estrogen replacement therapy on hemostatic variables associated with venous thrombosis: a randomized, placebo-controlled study in postmenopausal women - PubMed

Vaginal administration of estradiol: effects of dose, preparation and timing on plasma estradiol levels - PubMed

Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population - PubMed

Changes in menopause-specific quality of life between women with transdermal estradiol versus oral estrogens: results of a randomized controlled trial - PubMed

Hormoonsuppletietherapie en het risico op veneuze trombo-embolie | Stichting Geneesmiddelenbulletin

Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases - PubMed

Effects of estradiol administration on brain activation and anhedonia in perimenopausal women: A pharmaco-fMRI study - PubMed

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Prices
Dosage & pack size	Price
Mirena IUD 1 pc	£195.00

Mirena levonorgestrel IUD helps with

Discover how it works

A personal treatment plan for your symptoms

80% of women in menopause experience symptoms. Fortunately, you can do something about them. Start your consultation and receive a personal treatment plan from a doctor.

Man in a white medical coat typing on a laptop at a desk by a window with a blurred outdoor view in soft daylight

1
Complete a medical questionnaire
At your own pace, you complete the comprehensive medical questionnaire to outline your situation and treatment preferences. Following this, you finalise the ID check and pay 43 pounds for the treatment plan.
2
Get a treatment plan
Within 48 hours, the doctor will develop a personalised treatment plan for the first three months, tailored to your symptoms, medical condition, and treatment preferences. You then decide which products you wish to order and complete the payment.
Any questions? Just ask the doctor in the chat. We will save your recommendation for 30 days, giving you plenty of time to think it over.
3
Start your treatment
Within three days, you will receive the products from the pharmacy at home, along with a complimentary nutrition and lifestyle guide filled with tips from our hormone therapist. This way, you can promptly begin your treatment. During the treatment, the doctor will follow up with you, and you can also ask questions via the chat.

Frequently asked questions

Will my treatment be covered?

What is a consultation and how does it work?

How long will it take to receive my order?

Are there delivery charges?

Can I change, cancel or return my order?

Unfortunately, once an order has been placed, it cannot be changed. If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.