Mysimba is a weight-loss medication designed to assist with weight reduction if you are dealing with overweight or obesity, including during menopause. It is non-hormonal and contains two active ingredients: bupropion and naltrexone. These ingredients target specific areas of the brain involved in appetite and reward, potentially reducing cravings and making it easier to lose weight. Mysimba is intended for individuals with a BMI of 30 or higher, or from 27 if you have additional risk factors such as type 2 diabetes, cardiovascular diseases, or sleep apnoea. It is available by prescription only.
Mysimba




In short
- For overweight or obesity during menopause
- May help with binge eating, mood swings, and fatigue
- Tablet containing bupropion and naltrexone (non-hormonal)
- Only suitable for a BMI of 30 or higher, or from 27 with additional risk factors
- Prescription medication
What is Mysimba?
What can you expect from Mysimba?
Mysimba works by suppressing your appetite and enhancing your sense of fullness. It is taken as a daily tablet. You can generally expect to notice an effect on your weight within a few weeks to months, particularly when combined with healthy eating and regular physical activity.
When should I use Mysimba?
- Take Mysimba daily as per the dosage schedule prescribed by your doctor.
- The dosage is gradually increased over several weeks to reach the appropriate level.
- Mysimba is only suitable if your BMI is 30 or higher, or from 27 with additional health risks.
- It is not suitable for women who are pregnant or breastfeeding.
The package leaflet contains all the necessary information about this product. Ensure you read the leaflet before using the medication.
For which symptoms is Mysimba used?
- Mysimba is used for overweight or obesity.
- It may also help with symptoms such as binge eating, mood swings, and fatigue associated with being overweight.
Do not use Mysimba if you:
- Are pregnant or breastfeeding.
- Have high blood pressure that is not controlled.
- Have epilepsy or an increased risk of seizures.
- Have an eating disorder (such as bulimia or anorexia).
- Have a severe liver or kidney condition.
- Are allergic to bupropion, naltrexone, or other ingredients in Mysimba.
- Have recently stopped using alcohol, sedatives, or certain other medications.
- Are taking certain medications, such as monoamine oxidase inhibitors (MAO inhibitors) or opioids.
- You may drive or operate machinery if you feel well, but take care if you experience dizziness or concentration problems.
Always consult your doctor if you are taking other medications, as there may be potential interactions.
Possible side effects of Mysimba
Common (in 1 to 10 out of 100 people):
- Nausea
- Vomiting
- Constipation
- Abdominal pain
- Headache
- Dizziness
- Insomnia
- Dry mouth
- Decreased appetite
Uncommon (in 1 to 10 out of 1,000 people):
- Anxiety
- Mood swings
- Increased blood pressure
- Palpitations
- Sweating
- Skin rash
Rare (in fewer than 1 out of 1,000 people):
- Seizures (epileptic attack)
- Severe allergic reactions
In rare cases, these side effects can lead to serious conditions, such as seizures or severe allergic reactions. Always contact a doctor immediately in such cases.
For a complete list of side effects, refer to the package leaflet.
Patient Information Leaflet
Read the patient information leaflet carefully before using Mysimba.
Mysimba helps with
Frequently asked questions
Will my treatment be covered?
This depends on your health insurance provider. We recommend you check with your own insurance company. Supplements are not usually covered.
What is a consultation and how does it work?
During the consultation, you will complete a comprehensive medical questionnaire. You can also state your preferred type of treatment. Based on your answers, a doctor will prepare a treatment plan for you within 48 hours. If you approve this plan, a pharmacy will dispatch the products to your home within 3 days.
How long will it take to receive my order?
Our partner pharmacies will dispatch your order within 3 days. You can then typically start your treatment straight away.
Are there delivery charges?
For prescription medicines, delivery is included in the price. For over-the-counter products, there is a delivery charge of £4.21. We offer free delivery on orders over £40. If your order includes both, delivery is free.
Can I change, cancel or return my order?
Unfortunately, once an order has been placed, it cannot be changed. If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.