Hormone therapy

Trisequens

Q: Will my treatment be covered?

This depends on your health insurance provider. We recommend you check with your own insurance company. Supplements are not usually covered.

Q: What is a consultation and how does it work?

During the consultation, you will complete a comprehensive medical questionnaire. You can also state your preferred type of treatment. Based on your answers, a doctor will prepare a treatment plan for you within 48 hours. If you approve this plan, a pharmacy will dispatch the products to your home within 3 days.

Q: How long will it take to receive my order?

Our partner pharmacies will dispatch your order within 3 days. You can then typically start your treatment straight away.

Q: Are there delivery charges?

For prescription medicines, delivery is included in the price. For over-the-counter products, there is a delivery charge of £ 4.21. We offer free delivery on orders over £4 0. If your order includes both, delivery is free.

Q: Can I change, cancel or return my order?

Unfortunately, once an order has been placed, it cannot be changed . If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.

Tablet

In short

For symptoms such as hot flushes, poor sleep, and vaginal dryness.
May help with mood swings, night sweats, and forgetfulness.
Tablet containing bioidentical and synthetic hormones
Designed for women with a uterus experiencing menopausal symptoms
Prescription-only medication

What is Trisequens?

Trisequens is a hormone therapy that may help alleviate menopausal symptoms such as hot flushes, poor sleep, vaginal dryness, and mood swings. Trisequens contains two types of hormones in varying compositions: bioidentical estradiol (similar to the natural oestrogen in your body) and synthetic norethisterone (a form of progesterone). This combination replenishes the deficiency of female hormones and helps reduce menopausal symptoms. Trisequens is specifically designed for women with a uterus. This medication is available by prescription only.

What can you expect from Trisequens?

When should I use Trisequens?

Take one tablet daily as per your doctor’s instructions
Take the tablets at the same time each day.
Note: Only use if you have a uterus.
Not suitable if you are pregnant or breastfeeding.

The package leaflet contains all the information about this product. Read the leaflet before using the product.

For which symptoms is Trisequens used?

Hot flushes
Poor sleep
Vaginal dryness

Trisequens may also help with:

Mood swings
Fatigue
Irritability

Do not use Trisequens if you:

Are allergic to estradiol, norethisterone, or other ingredients
Have or have had blood clots (such as thrombosis or pulmonary embolism)
Have or have had liver disease
Have or have had breast cancer or another hormone-sensitive cancer
Have unexplained vaginal bleeding
Have severe heart or vascular diseases

Inform your prescribing doctor if you are taking other medications. This medication may interact with other drugs.

Possible side effects of Trisequens

Common (affecting 1 to 10 in 100 people):

Headache
Abdominal pain
Nausea
Tender breasts
Breakthrough bleeding or spotting (light bleeding between periods)

Uncommon (affecting 1 to 10 in 1,000 people):

Mood changes
Weight gain
Fluid retention
Migraine
Back pain

Rare (affecting fewer than 1 in 1,000 people):

Skin rash
Gallbladder disorders
Increased risk of blood clots

In rare cases, these side effects can lead to serious conditions, such as blood clots. Always contact a doctor immediately in such cases.

For a complete list of side effects, refer to the package leaflet.

Risks of hormone therapy

Using medication can carry risks, and this also applies to hormone therapy:

Increased risk of breast and uterine cancer with long-term use.
Slightly increased risk of cardiovascular diseases (such as thrombosis).
Slightly increased risk of stroke. Smoking, high blood pressure, or high cholesterol further increase this risk.

The risks are primarily associated with long-term use or for women who start treatment later in menopause. A full overview of potential risks for this medication can be found in the package leaflet.

Scientific sources

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions - PubMed

Cognitive health after menopause: Does menopausal hormone therapy affect it? - PubMed

Impact of estrogens on resting energy expenditure: A systematic review - PubMed

Cognition and mental health in menopause: A review - PubMed

The role of estrogen in female skeletal muscle aging: A systematic review - PubMed

Oestrogen-based therapies for menopausal symptoms - PubMed

The role of menopausal symptoms on future health and longevity: A systematic scoping review of longitudinal evidence - PubMed

Menopause Transition: Signs, Symptoms, and Management Options | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic

Menopausal Hormone Therapy and Cardiovascular Disease: The Role of Formulation, Dose, and Route of Delivery - PubMed

Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause : A Systematic Review - PubMed

Menopausal Hormone Replacement Therapy and Reduction of All-Cause Mortality and Cardiovascular Disease: It Is About Time and Timing - PubMed

Trisequens helps with

Vaginal dryness

Hot flushes

Poor sleep

Frequently asked questions

Will my treatment be covered?

What is a consultation and how does it work?

How long will it take to receive my order?

Are there delivery charges?

Can I change, cancel or return my order?

Unfortunately, once an order has been placed, it cannot be changed. If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.

Trisequens

In short

Medically reviewed by

Patient Information Leaflet

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Trisequens helps with

Frequently asked questions