Utrogestan is a medication containing the hormone progesterone. This is a bioidentical hormone, which is also naturally present in the body. The capsules are used as part of hormone replacement therapy for menopausal symptoms. Utrogestan is typically prescribed as a supplement to oestrogen hormone replacement therapy for women with a uterus. It complements the effects of oestrogen, protects the uterine lining from excessive growth, and reduces the risk of uterine cancer. It may also assist with poor sleep. Utrogestan is available by prescription only.
Utrogestan




In short
- Protects against, among other things, heavy bleeding during oestrogen supplementation
- May help improve poor sleep
- Capsule containing bioidentical hormone progesterone
- For women with a uterus undergoing oestrogen supplementation
- Prescription-only medication
What is Utrogestan?
What can you expect from Utrogestan?
Utrogestan is a hormone replacement therapy in capsule form. It supplements the progesterone deficiency that can occur during menopause and oestrogen supplementation. Most people notice a reduction in symptoms within a few weeks, though the effect can vary from person to person. Utrogestan only works when used in combination with oestrogen therapy. It protects the uterine lining from excessive growth caused by oestrogen.
When should I use Utrogestan?
- Use Utrogestan daily as directed by your doctor, usually in combination with oestrogen supplementation.
- Take the capsules orally, following your doctor’s advice.
The package leaflet contains all the information about this product. Please read the leaflet before using the product.
For which symptoms is Utrogestan used?
This medication is specifically used to prevent heavy menstrual bleeding and to maintain a healthy uterine lining during oestrogen supplementation.
It may also help with:
- Poor sleep
Do not use Utrogestan if you:
- Are allergic to progesterone or any of the other ingredients
- Are pregnant or breastfeeding
- Have severe liver conditions
- Have (or have had) blood clots or thrombosis
- Have unexplained vaginal bleeding
- Have certain types of cancer (such as breast cancer or uterine cancer)
- Are taking certain other medications that are incompatible with Utrogestan (refer to the leaflet for a complete list)
- Are unsure about combining it with other medications; consult your doctor
- Do not have a uterus, unless specifically prescribed by your doctor
Possible side effects of Utrogestan
Common (affecting 1 to 10 out of 100 people):
- Drowsiness
- Dizziness
- Headache
- Tender breasts
- Irregular menstruation
- Abdominal pain
Uncommon (affecting 1 to 10 out of 1,000 people):
- Nausea
- Diarrhoea
- Fatigue
- Mood changes
- Skin reactions
Rare (affecting fewer than 1 out of 1,000 people):
- Allergic reactions
- Jaundice
- Blood clots
In rare cases, these side effects can lead to serious symptoms, such as difficulty breathing, facial swelling, jaundice (yellowing of the skin or eyes), or signs of thrombosis (sudden pain, swelling, or redness in a leg, chest pain, shortness of breath). Always contact a doctor immediately if you experience these symptoms.
Most women experience few or mild side effects. The package leaflet contains a complete list of possible side effects.
Risks of hormone replacement therapy
The use of medication carries risks, and this also applies to hormone replacement therapy:
- Increased risk of breast cancer and uterine cancer with long-term use.
- Slightly increased risk of cardiovascular disease (such as thrombosis).
- Slightly increased risk of stroke. Smoking, high blood pressure, or high cholesterol further increase this risk.
The risks are primarily associated with long-term use or for women who begin treatment later in menopause. The package leaflet provides a complete overview of the potential risks of this medication.
Scientific sources
Menopausal hormone therapy and women's health: An umbrella review - PubMed
Management of Menopausal Symptoms: A Review - PubMed
Hormone therapy for sexual function in perimenopausal and postmenopausal women - PubMed
Metabolism of progestogens used for contraception and menopausal hormone therapy - PubMed
Progestogens in Menopausal Hormone Therapy: A Double-Edged Sword - PubMed
Medically reviewed by

Patient Information Leaflet
Read the patient information leaflet carefully before using Utrogestan.
Utrogestan helps with
Frequently asked questions
Will my treatment be covered?
This depends on your health insurance provider. We recommend you check with your own insurance company. Supplements are not usually covered.
What is a consultation and how does it work?
During the consultation, you will complete a comprehensive medical questionnaire. You can also state your preferred type of treatment. Based on your answers, a doctor will prepare a treatment plan for you within 48 hours. If you approve this plan, a pharmacy will dispatch the products to your home within 3 days.
How long will it take to receive my order?
Our partner pharmacies will dispatch your order within 3 days. You can then typically start your treatment straight away.
Are there delivery charges?
For prescription medicines, delivery is included in the price. For over-the-counter products, there is a delivery charge of £4.21. We offer free delivery on orders over £40. If your order includes both, delivery is free.
Can I change, cancel or return my order?
Unfortunately, once an order has been placed, it cannot be changed. If you have ordered the wrong product, or wish to change or cancel your order, please contact our customer service team immediately. Over-the-counter products can only be cancelled if they have not yet been prepared or dispatched by the pharmacy. Prescription medicines can be cancelled if they have not yet been assessed by a doctor. Returns are only accepted for over-the-counter products in their original unopened and undamaged packaging, within 14 days of dispatch.