Women going through menopause are at a higher risk of insulin resistance. Insulin resistance is when cells in your body don't respond well to the hormone insulin. What exactly is insulin? What makes menopausal women prone to insulin resistance? And how can you tell if you have insulin resistance? Our menopause specialist, Suzanne Rouhard, will explain it to you in this article.
By the way, insulin resistance is not the end of the world. You can reverse it.
When you eat, your blood sugar (glucose) rises. This prompts your pancreas to release a hormone called insulin. Insulin plays a crucial role in regulating blood sugar levels by transferring glucose from the blood to the cells, where it is used as a source of energy.
When sugar (carbohydrates) from food enter the bloodstream, insulin enables cells to break it down and produce energy.
Insulin resistance is when your cells stop responding well to insulin. When this happens, more insulin is needed to transport the same amount of glucose to the cells. The result is a higher level of insulin in your blood. If your cells become resistant to insulin, it leads to elevated blood glucose levels. Over time, chronic insulin resistance can lead to various health issues, including type 2 diabetes, heart disease, obesity as well as hot flashes.
Here are signs that indicate that you might be suffering from insulin resistance:
The female sex hormone oestrogen is involved in the regulation of metabolic processes. When oestrogen levels fluctuate and drop in the years leading up to menopause, your body can become less responsive to insulin. This explains why women are more prone to insulin resistance during perimenopause.
Other factors, which may or may not be linked to menopause, may also cause an increased risk of insulin resistance, such as loss of muscle mass (your muscles consume glucose for energy), weight gain and belly fat, stress (the stress hormone cortisol has been shown to affect glucose metabolism) and chronic inflammation in the body.
→ Studies have shown that women with insulin resistance are more likely to develop leptin resistance, and vice versa. Signs of leptin resistance.
Fortunately, there are ways to combat insulin resistance. According to some professionals, insulin resistance can even be completely reversed. How? Through diet and exercise.
Do you think you could have insulin resistance? Then talk to a doctor. A doctor can diagnose insulin resistance and help you take the necessary steps to correct it.
Yaribeygi H, Maleki M, Butler AE, Jamialahmadi T, Sahebkar A. (2022). Molecular mechanisms linking stress and insulin resistance. PMID: 35368460.
Monica De Paoli, Alexander Zakharia, Geoff H. Werstuck. (2021). The Role of Estrogen in Insulin Resistance: A Review of Clinical and Preclinical Data. https://www.sciencedirect.com
Australian Menopause Centre. How to Live with Insulin Resistance https://www.menopausecentre.com.au/information-centre/articles/how-to-live-with-insulin-resistance/
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). (2018). Insulin Resistance & Prediabetes https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
Insulin resistance (or prediabetes) is a condition that should be taken as a warning sign. Without treatment, prediabetes is likely to develop into type 2 diabetes. Insulin resistance increases the chance of developing type 2 diabetes. Prediabetes means that your blood sugar level is higher than usual, but not high enough for you to be diagnosed with type 2 diabetes. Over time, though, insulin resistance can get worse and lead to type 2 diabetes. Note: if you have insulin resistance, your blood sugar is still within a normal range. The Homa IR blood test can be used to determine if you have insulin resistance.
Insulin resistance increases the chance of developing type 2 diabetes. It can also cause hot flashes, memory problems, weight gain, high cholesterol, high blood pressure and heart problems.
Your GP can check your blood sugar with a finger-prick blood test (blood glucose monitor).