Xenical
- Weight loss medicine
- Take capsule with food
- Can cause diarrhoea with high-fat foods
- This medicine requires a doctor’s prescription. Add the product to your shopping cart to start an (online) consultation.
As you go through menopause, your body shape may change. This is because the menopausal transition causes a shift in fat distribution: fat that is present on your buttocks and thighs may move to your belly. In addition, your metabolism slows down. This causes you to gain weight more easily and makes it more difficult to lose the weight you gained.
Xenical is a prescription weight loss treatment for people who are seriously overweight or obese. The active ingredient prevents part of the fat in your food from being absorbed. As a result, your calorie intake will drop, resulting in weight loss. Instead of being stored in the body, the undigested fat (about one-third of the fat in the food you eat) leaves the body through bowel movements. However, you should make sure to choose low-fat foods more often, as eating foods higher in fat causes side effects such as diarrhoea.
Note: Xenical works best when it is used along with a reduced-calorie diet. If you have been unable to lose 5% of your body weight after 16 weeks of treatment, then Xenical is not the right weight loss medicine for you.
Always use Xenical exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Dosage
The usual dose of Xenical is:
- Adults: one 120-mg capsule taken with each of the three main meals per day.
The capsule can be taken immediately before, during a meal or up to one hour after a meal. It should be swallowed with water.
Instructions for use
Xenical should be taken with a well-balanced, calorie-controlled diet that is rich in fruit and vegetables and contains an average of 30% of the calories from fat. Your daily intake of fat, carbohydrate and protein should be distributed over three meals. To gain optimal benefit, avoid the intake of food containing fat between meals, such as biscuits, chocolate and savoury snacks.
Xenical only works in the presence of dietary fat. Therefore, if you miss a main meal or if you have a meal containing no fat, Xenical need not be taken.
Tell your doctor if, for any reason, you have not taken Xenical exactly as prescribed. Otherwise, your doctor may think that it was not effective or well tolerated and may change your treatment unnecessarily. Your doctor will discontinue the treatment with Xenical after 12 weeks if you have not lost at least 5% of your body weight as measured at the start of the treatment.
If you take more or less Xenical than you should
If you take more capsules than you have been told to take, contact a doctor as you may need medical attention.
If you miss a dose, take it as soon as you remember provided this is within one hour of your last meal. If more time has passed, then skip the missed dose and continue with your regular dosing schedule. If you have missed several doses, please inform your doctor and follow the advice given to you.
Xenical is not suitable for everyone. Do not take this medicine if:
- You are allergic (hypersensitive) to orlistat or any other ingredient in this medicine.
- You have chronic malabsorption syndrome (insufficient absorption of nutrients from alimentary tract).
- You have cholestasis (liver disorder).
- You are breastfeeding.
- Xenical is not suitable for use in children.
When should Xenical be used with caution?
Xenical should be used with extreme caution in the following situations:
Weight loss may affect the dose of medicines taken for other conditions (e.g., high cholesterol or
diabetes). Be sure to discuss these and other medicines you may be taking with your doctor. Losing weight may mean you need adjustments to the dose of these medicines.
This medicine can cause harmless changes in your bowel habits, such as fatty or oily stools, due to the elimination of undigested fat in your faeces. The possibility of this happening may increase if Xenical is taken with a diet high in fat. In addition, your daily intake of fat should be distributed evenly over three main meals because if Xenical is taken with a meal very high in fat, the possibility of gastrointestinal effects may increase.
The use of an additional contraceptive method is recommended to prevent possible failure of oral
contraception that could occur in case of severe diarrhoea.
The use of Xenical may be associated with renal stones in patients suffering from chronic kidney
disease. Inform your doctor whether you suffer from problems with your kidney.
Pregnancy and breastfeeding
Taking Xenical during pregnancy is not recommended.
You must not breastfeed your infant during treatment with Xenical. This is because it is not known if Xenical passes into breast milk.
Other medicines and Xenical
Xenical is known to interact with some medicines. Xenical may modify the activity of:
- Anticoagulant drugs (e.g., warfarin). Your doctor may need to monitor your blood coagulation.
- Ciclosporin. Co-administration with ciclosporin is not recommended. Your doctor may need to monitor your ciclosporin blood levels more frequently than usual.
- Iodine salts and/or levothyroxine. Cases of hypothyroidism and/or reduced control of hypothyroidism may occur.
- Amiodarone. Ask your doctor for advice.
Xenical reduces the absorption of supplements of some fat-soluble nutrients, particularly beta-carotene and vitamin E. You should therefore follow your doctor’s advice in taking a well-balanced diet rich in fruit and vegetables. Your doctor may suggest you take a multivitamin supplement.
Xenical may unbalance an anticonvulsant treatment, by decreasing the absorption of antiepileptic
drugs, thus leading to convulsions. Please contact your doctor if you think that the frequency and/or severity of the convulsions have changed when Xenical together with antiepileptic drugs.
For more warnings about the use of Xenical, please see the package leaflet.
Like all medicines, Xenical can cause side effects, although not everyone gets them. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Xenical.
The majority of unwanted effects related to the use of Xenical result from its local action in your
digestive system. These symptoms are generally mild, occur at the beginning of treatment and are
particularly experienced after meals containing high levels of fat. Normally, these symptoms disappear if you continue treatment and keep to your recommended diet.
Very common side effects (may affect more than 1 in 10 users)
- Headache.
- Abdominal pain/discomfort.
- Urgent or increased need to open the bowels.
- Flatulence (wind) with discharge.
- Oily discharge, oily or fatty stools.
- Liquid stools.
- Low blood sugar levels (experienced by some people with type 2 diabetes).
Common side effects (may affect up to 1 in 100 users)
- Rectal pain/discomfort.
- Soft stools.
- Incontinence (stools).
- Bloating (experienced by some people with type 2 diabetes).
- Tooth/gum disorder.
- Irregularity of menstrual cycle.
- Tiredness.
For a list of less common side effects, please see the package leaflet. Consult a doctor if the side effects are severe or if you experience side effects that are not listed on the leaflet.
The following ingredients are in this medicine:
- The active substance is orlistat. Each capsule contains 120 mg of orlistat.
- The other ingredients are cellulose microcrystalline (E460), sodium starch glycolate, povidone (E1201), sodium lauryl sulphate, talc. The capsule shell consists of gelatine, indigo carmine (E132), titanium dioxide (E171) and edible printing ink.
How does having an online consultation with a doctor work?
1. Choose your preferred treatment
Select your preferred treatment and complete the accompanying digital medical questionnaire.
2. Your order request is reviewed by a doctor
A doctor will review your order within 48 hours and forward the prescription to a pharmacy.
3. Your order is shipped by the pharmacy
Your order will be shipped to your home within three to five working days free of charge.
Reviewed by
Arco Verhoog,
Pharmacist
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Registration number:
BIG-register: 19065378617
BIG-register: 19065378617
Last checked:
29-08-2024
29-08-2024
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still valid
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